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ea0037ep1094 | Endocrine tumours | ECE2015

Plasma chromogranin A and chromogranin B concentrations in untreated patients with mid gut carcinoid and their biochemical response to octreotide

Armstrong Lee , Rea Teresa , Johnston Brian , McCance David

We measured chromogranin A (CgA) and chromogranin B (CgB) in 36 patients, recently confirmed to have a midgut carcinoid tumour (MGC), prior to the commencement of octreotide treatment. Blood samples were taken before and after a bolus injection of 50 μg octreotide. There were 21 males, 15 females, age range 28–76 median 61 years.Basal CgA, expressed as times the upper limit of normal (ULN) ranged from 333.3 to 0.5 ULN. Basal CgB ranged from 33....